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Moringa leaves as anti-inflammatory


a. inflammation

Inflammation is a complex biological response of vascular tissues on their dangers, such as pathogens, damage cells, or irritants. This is an attempt of self-protection of our body to eliminate stimuli cause injury and initiation process of tissue healing. If the inflammation is not there, then the wounds and infections would not heal and will experience more severe damage. However, uncontrolled inflammation can also cause disease, such as fever, atherosclerosis, and reumathoid arthritis. (Gard, 2001)


Inflammation can be divided into acute and chronic inflammation. Acute inflammation is the initial response by the body of harmful substances and continues to increase in line with the increased movement of plasma and leukocytes from the blood to the wound tissue. Biochemical reaction chain propagating and maturation of the immune response, including the vascular system, immune system, and various cells that exist in the scar tissue. Chronic inflammation is inflammation that in the long run, lead to an increase in turnover of cell types that exist in places characterized by inflammation and tissue damage and the closure of the inflammatory process. (Gard, 2001)


Inflammation is a response of tissues to physical or chemical stimuli that damage cells. These stimuli cause the release of inflammatory mediators such as histamine, serotonin, bradykinin, and prostaglandins, which cause an inflammatory reaction in the form of heat, pain, redness, swelling, and accompanied it to malfunction. Cell damage associated with inflammation of the membranes affects cell membranes that cause leukocytes secrete lysosomal enzymes and arachidonic acid., Subsequently removed from compound-compound earlier. Hiking cyclooxygenase (COX) on the metabolism of arachidonic produce prostaglandins that have an effect on blood vessels, nerve endings, and the cells involved in inflammation. (Katzung, 2004). That is why when we feel the pain of inflammation.


b. Anti-inflammatoryAnti-inflammatory drugs are able to eliminate the inflammation is caused not because microorganisms (non-infectious), but arising as a response to tissue injury and infection. Agents have anti-inflammatory properties such additional relieve pain (analgesics), and fever (Antipyretic). After doing research for drugs that efektiftif and minimal side effects, then introduced drugs non-steroidal anti-inflammatory or NSAIDs (Non Steroidal Drug Antiinflamatory) having the effects of a powerful anti-inflammatory. NSAIDs have analgesic efficacy (pain relievers), antipyretics (fever), and anti-inflammatory (anti-inflammatory). The term "non-steroidal" is used to distinguish between types of these drugs with steroids, which also has a similar efficacy. NSAIDs are not classified as drugs kind of narcotic.


How NSAIDs work is based on the inhibition of COX-1 isoenzyme (cyclooxygenase-1) and COX-2 (cyclooxygenase-2). The cyclooxygenase enzyme plays a role in triggering the formation of prostaglandin and thromboxane from arachidonic acid. With this isoenzyme inhibition, the prostaglandins that cause inflammation in the form of heat, pain, redness, swelling, and impaired function accompanied it was not formed.


Moringa plant parts have substantial anti-inflammatory activity. For example, a root extract showed significant anti-inflammatory activity in the carrageenan-induced rat foot edema (Ezeamuzie et al, 1996; .. Khare et al, 1997). In addition, n-butanol Moringa seed extracts showed anti-inflammatory activity against ovalbumin-induced airway inflammation in mice (Mahajan et al., 2009).


c. Ingredients Natural Anti-Inflammatory Moringa


Vitamin A, Vitamin B1 (Thiamin), Vitamin C, Vitamin E, Arginine, Beta-sitosterol, Acid Caffeoylquinic, Calcium, Chlorophyll, Copper, cystine, Omega 3, Omega 6, Omega 9 Fiber, Glutathione, histidine, Indole Acetic Acid , indole acetonitrile, isoleucine, Kaempferal, Leucine, Magnesium, oleic acid, Phenylalanine, Potassium, Quercetin, Rutin, Selenium, stigmasterol, Sulfur, Tryptophan, Tyrosine, Zeatin, Zinc.

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